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Facility: Imagenetics Building
Location: Sioux Falls, SD
Address: 1321 W 22nd St, Sioux Falls, SD 57105, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Starting Rate: $27.50/hr
The Molecular Genetics lab (MGL) located in the Imagenetics building in Sioux Falls, South Dakota. The variant analyst will focus on supporting the laboratory directors and laboratory genetic counselors in reviewing, curating, and maintaining variant databases. Responsibilities include, but not limited to, updating workflows for variant curation, managing curation databases and submitting variants to CLINVAR (improves our lab’s profile). This position will also support variant curation for chromosomal microarray (CMA), whole genome sequencing (WGS), and cancer testing. There could also be opportunities to contribute to outcomes research and development activities (translating research to clinical assays).
The Genomic Variant Analyst will support the Sanford Medical Genetics lab in review and documentation of genomic variants following practice guidelines under the direction of the Laboratory Directors. Will also support the Imagenetics program with outcomes research. The Analyst will investigate and curate genetic sequencing variants. Assist with the day to day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational studies. Establish the process for classifying variants, including review and update previous sequence variant classifications. Support clinical outcomes research.
Critically evaluate and interpret genetic sequence variation identified through diagnostic or predictive clinical genetic testing, including next generation sequencing and copy number arrays. Author core SOPs. Work in conjunction with laboratory directors to ensure consistent sequence variant classification. Investigate and rectify, if possible, discrepancies in variant classification. Support laboratory directors in evaluating relevance of genes to human disease. Deliver and communicate results and scientific presentations to internal and external scientific personnel. Key contributor to high-quality, regulatory documents and scientific publications. Help maintain variant databases. May participate in research and development depending on experience. Additional tasks as required/requested.
Masters degree required; PhD preferred. Or equivalent, in a clinical laboratory science, genetics, or molecular biology preferred.
Minimum three years combined work experience and education required.
Prior experience in a diagnostic laboratory, clinical report writing, and familiarity with human mutation databases, genome browsers, and HGVS nomenclature.
Screening and diagnostic experience strongly preferred
Hands-on experience in NGS-based testing, including
bioinformatics experience is a plus.
Knowledge of CLIA & CAP guidelines in clinical validation a plus.
ASCP certification or equivalent a plus.
Sanford Health offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, sick leave and paid time off. To review your benefit eligibility, visit https://sanfordhealth.jobs/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to email@example.com .
Sanford Health has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Job Function: Allied Health
Req Number: R-75055